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SCK-CEN

Senior Scientist for preclinical studies - radiobiology

At SCK-CEN

Published on Jobat.be 9 days ago

SCK•CEN is one of the largest research institutions in Belgium. Every day, more than 700 employees dedicate themselves to developing peaceful applications of radioactivity. Our developments have already resulted in a long list of innovative and forward-looking applications for the medical world, industry and the energy sector. We are renowned for our expertise world-wide.
 
In the course of our work, there are three main research topics:
•The safety of nuclear installations
•The well-considered management of radioactive waste
•Human and environmental protection against ionising radiation
 
SCK•CEN collaborates with numerous research partners both at home and abroad.
 
The work performed by SCK•CEN has a direct effect upon various aspects of our daily life. Besides our work as a research centre, we also organise training courses and offer specialist services including  consultancy.
 

Senior Scientist for preclinical studies - radiobiology

Job description

The Belgian Nuclear Research Centre, SCK•CEN, has 60 years of experience in fundamental and applied research in peaceful applications of radioactivity. Developing a CRO for radiopharmaceutical services, we are committed to providing an outstanding research and services to our customers. Furthermore, we offer excellent training and career development opportunities, encouraging growth from within our talented workforce.


We have a vacancy within our preclinical monitoring program for an experienced preclinical research associate to join our Radiobiology Team.


This is a great opportunity to join a progressive and developing CRO in the radiopharmaceutical field. Your work will be devoted to setting up and coordinating the preclinical programs at in vitro and in vivo level. Making an impact in radiodiagnostics and targeted radiotherapy, training and development will be provided  to progress in your career. The SCK•CEN Radiobiology Unit offers a dynamic environment that will allow you to develop your current skill set and experience.
 

More specifically, you will have the following responsibilities:

  • Actively participate in the development of the preclinical programs in a new radioactive facility within the Radiobiology Unit devoted to in vitro and in vivo research and CRO activities
  • Develop toxicology strategies and key safety criteria for drug development programs to support each program’s progression through different stages, including “Go/No Go” decisions in preparation of the IMPD appropriate documentation required for the approval of clinical trials
  • Ensure appropriate and timely design, initiation, execution and reporting of preclinical studies (exploratory and GLP)
  • Represent the preclinical safety assessment function on development teams and support the design and implementation of preclinical programs
  • Ensure compliance of the preclinical study protocol requirements within the appropriate regulatory and ethical guidelines and standards
  • Prepare and present the preclinical protocols to the Ethical Committee and the Animal Welfare Committee
  • Help identify and hire appropriate consultants where needed

Profile

  • MSc, PhD, MD, or equivalent in toxicology, pathology or (radio)pharmacology (pharmacokinetics, pharmacodynamics)
  • Excellent knowledge of Good Laboratory Practice (GLP) and relevant professional experience of conducting preclinical trials in general
  • Experience of performing start-up preclinical procedures and routine monitoring
  • 5+ years of toxicology and/or pathology experience in pharmaceutical/biotechnology drug development
  • Strong interest in research and the ability to initiate, collaborate and lead teams to address scientific issues
  • Ability to manage multiple priorities across various preclinical trials in a multidisciplinary environment
  • Experience interacting with health authorities
  • Knowledge in radiopharmaceuticals is an added value
  • Excellent interpersonal and organisational skills
  • Excellent communication, organizational and leadership skills with an ability to work both independently and in a multidisciplinary team
  • Fluent in English. Knowledge of Dutch is an asset. Non-Dutch speakers should be prepared to acquire a minimum knowledge of the Dutch language.

Please note that SCK • CEN is closed for 3 weeks in July and August. The selection will take place at the earliest in September 2018.

Offer

  • A challenging and varied job
  • Opportunities for self-development in an absorbing, international research environment
  • Extensive training opportunities within and outside your area of expertise
  • An attractive remuneration package with non-statutory benefits
  • Located in wooded area to ensure you a traffic jam free environment
Geel - Herentals

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Characteristics

Requirements

  • Master (University or Higher Education Long Type)
  • At least 5 years experience
  • Dutch, French, English

Offer

  • Permanent
  • Full-time

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